3 charged for major theft organization targeting luxury vehiclesMan arrested for DUI after slamming into Port Charlotte home’s garage
LEHIGH ACRES 3 charged for major theft organization targeting luxury vehicles Three men, one from Lehigh Acres, has been charged for their role in a major theft organization targeting luxury vehicles.
port charlotte Man arrested for DUI after slamming into Port Charlotte home’s garage The North Port Police Department has arrested a man accused of DUI and crashing into a Port Charlotte home’s garage.
CAPE CORAL New information on nurse accused of starving premature baby New information has been released about what happened behind closed doors when a nurse allegedly starved a premature baby.
BONITA SPRINGS World’s largest bounce castle to spring into Bonita Springs The Big Bounce America, the world’s largest inflatable bounce castle is set to appear in Bonita Springs.
palmdale Gatorama owner bitten during alligator feeding show Gatorama owner Allen Register was sent to hospital after being bitten by an alligator during a feeding show.
CAPE CORAL Man accused of Cape Coral DUI accident with serious injuries A man has been arrested after allegedly causing an accident with injuries while driving under the influence in Cape Coral.
wink news Web Exclusive: Rachel Cox-Rosen’s Construction Heads Up As construction may dampen your commute, WINK News traffic anchor Rachel Cox Rosen knows the best way to traverse the roadways in this web-exclusive feature.
the weather authority Another warm afternoon for your Tuesday plans The Weather Authority is tracking a warm Tuesday afternoon with stray rain showers expected in our inland communities.
NORTH FORT MYERS Cape Coral man faces 16 charges after fleeing multiple traffic stops Marcus Selby, 24, is facing multiple charges after a dramatic series of events involving Cape Coral police and Florida Highway Patrol troopers.
SANIBEL Sanibel residents brace for traffic surge with new advisory and app aid Sanibel residents are bracing for increased traffic as the city issued a “heavy traffic advisory” for the entire week.
FGCU FGCU’s Casey Santoro battles back from Achilles injury FGCU women’s basketball player Casey Santoro is back on the floor after suffering an Achilles injury a season ago.
BABCOCK RANCH Heaviest Florida panther ever recorded located in Babcock Ranch Florida Fish & Wildlife Conservation Commission biologists recently captured and collared the heaviest Florida panther ever recorded.
Lee County deputies using VR for safe high-risk training scenarios The Lee County Sheriff’s Office has taken a significant step forward in training by incorporating virtual reality technology.
NAPLES FC Naples signs local soccer star Joffre followed his dream across continents after graduating from Gulf Coast. Now he’s back on the professional soccer pitch in his hometown.
FORT MYERS BEACH Fort Myers Beach businesses face floodplain compliance deadline Fort Myers Beach’s businesses face pressure to comply with floodplain regulations or leave the island by March 1.
LEHIGH ACRES 3 charged for major theft organization targeting luxury vehicles Three men, one from Lehigh Acres, has been charged for their role in a major theft organization targeting luxury vehicles.
port charlotte Man arrested for DUI after slamming into Port Charlotte home’s garage The North Port Police Department has arrested a man accused of DUI and crashing into a Port Charlotte home’s garage.
CAPE CORAL New information on nurse accused of starving premature baby New information has been released about what happened behind closed doors when a nurse allegedly starved a premature baby.
BONITA SPRINGS World’s largest bounce castle to spring into Bonita Springs The Big Bounce America, the world’s largest inflatable bounce castle is set to appear in Bonita Springs.
palmdale Gatorama owner bitten during alligator feeding show Gatorama owner Allen Register was sent to hospital after being bitten by an alligator during a feeding show.
CAPE CORAL Man accused of Cape Coral DUI accident with serious injuries A man has been arrested after allegedly causing an accident with injuries while driving under the influence in Cape Coral.
wink news Web Exclusive: Rachel Cox-Rosen’s Construction Heads Up As construction may dampen your commute, WINK News traffic anchor Rachel Cox Rosen knows the best way to traverse the roadways in this web-exclusive feature.
the weather authority Another warm afternoon for your Tuesday plans The Weather Authority is tracking a warm Tuesday afternoon with stray rain showers expected in our inland communities.
NORTH FORT MYERS Cape Coral man faces 16 charges after fleeing multiple traffic stops Marcus Selby, 24, is facing multiple charges after a dramatic series of events involving Cape Coral police and Florida Highway Patrol troopers.
SANIBEL Sanibel residents brace for traffic surge with new advisory and app aid Sanibel residents are bracing for increased traffic as the city issued a “heavy traffic advisory” for the entire week.
FGCU FGCU’s Casey Santoro battles back from Achilles injury FGCU women’s basketball player Casey Santoro is back on the floor after suffering an Achilles injury a season ago.
BABCOCK RANCH Heaviest Florida panther ever recorded located in Babcock Ranch Florida Fish & Wildlife Conservation Commission biologists recently captured and collared the heaviest Florida panther ever recorded.
Lee County deputies using VR for safe high-risk training scenarios The Lee County Sheriff’s Office has taken a significant step forward in training by incorporating virtual reality technology.
NAPLES FC Naples signs local soccer star Joffre followed his dream across continents after graduating from Gulf Coast. Now he’s back on the professional soccer pitch in his hometown.
FORT MYERS BEACH Fort Myers Beach businesses face floodplain compliance deadline Fort Myers Beach’s businesses face pressure to comply with floodplain regulations or leave the island by March 1.
This photo provided by Novartis shows Zolgensma. The one-time gene therapy developed by Novartis, Zolgensma, will cost $2.125 million. It treats a rare condition called spinal muscular atrophy, or SMA, which strikes about 400 babies born in the U.S. each year. The therapy, given in a one-hour infusion, was approved for children under age 2 and will be available within two weeks. (Novartis via AP) U.S. regulators have approved the most expensive medicine ever, for a rare disorder that destroys a baby’s muscle control and kills nearly all of those with the most common type of the disease within a couple of years. The treatment is priced at $2.125 million. Out-of-pocket costs for patients will vary based on insurance coverage. The medicine, sold by the Swiss drugmaker Novartis, is a gene therapy that treats an inherited condition called spinal muscular atrophy. The treatment targets a defective gene that weakens a child’s muscles so dramatically that they become unable to move, and eventually unable to swallow or breathe. It strikes about 400 babies born in the U.S. each year. The Food and Drug Administration on Friday approved the treatment, called Zolgensma, for all children under age 2 who are confirmed by a genetic test to have any of the three types of the disease. The therapy is a one-time infusion that takes about an hour. Novartis said it will let insurers make payments over five years, at $425,000 per year, and will give partial rebates if the treatment doesn’t work. The one other medicine for the disease approved in the U.S. is a drug called Spinraza. Instead of a one-time treatment, it must be given every four months. Biogen, Spinraza’s maker, charges a list price of $750,000 for the first year and then $350,000 per year after that. The independent nonprofit group Institute for Clinical and Economic Review, which rates the value of expensive new medicines, calculated that the price of the new gene therapy is justifiable at a cost of $1.2 million to $2.1 million because it “dramatically transforms the lives of families affected by this devastating disease.” ICER’s president, Dr. Steven D. Pearson, called the treatment’s price “a positive outcome for patients and the entire health system.” The defective gene that causes spinal muscular atrophy prevents the body from making enough of a protein that allows nerves that control movement to work normally. The nerves die off without the protein. In the most common type, which is also the most severe, at least 90% of patients die by age 2, and any still alive need a ventilator to breathe. Children with less-severe types become disabled more slowly and can live for up to a couple decades. Zolgensma works by supplying a healthy copy of the faulty gene, which allows nerve cells to then start producing the needed protein. That halts deterioration of the nerve cells and allows the baby to develop more normally. In patient testing, babies with the most severe form of the disease who got Zolgensma within 6 months of birth had limited muscle problems. Those who got the treatment earliest did best. Babies given Zolgensma after six months stopped losing muscle control, but the medicine can’t reverse damage already done. Evelyn Villarreal was one of the first children treated, at eight weeks. Her family, from Centreville, Virginia, had lost their first child to spinal muscular atrophy at 15 months. Two years later when Evelyn was born a test showed she also had the disease, so the family enrolled her in the gene therapy study at Nationwide Children’s Hospital in Columbus, Ohio. Evelyn is now 4½ years old and showing no muscle problems other than minor trouble standing up, said her mother, Elena Villarreal. She has been feeding herself for a long time, she draws and speaks well, and will be starting kindergarten in the fall. “She’s very active and goes to the playground a lot,” said Elena Villarreal. “She’s walking and even jumping.” It is too early to know how long the benefit of the treatment lasts, but doctors’ hopes are rising that they could last a lifetime, according to Dr. Jerry Mendell, a neurologist at Nationwide Children’s. Mendell led one of the early patient studies and is Evelyn’s doctor. “It’s beginning to look that way,” he said, because a few children treated who are now 4 or 5 still have no symptoms. Early diagnosis is crucial, so Novartis has been working with states to get genetic testing for newborns required at birth. It expects most states will have that requirement by next year. The FDA said side effects included vomiting and potential liver damage, so patients must be monitored for the first few months after treatment.