Your Health Now: Alzheimer’s Disease

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FORT MYERS, Fla.- With a large population of 65 and older, Southwest Floridians have a better chance of getting Alzheimer’s disease than most areas in the state.

As baby boomers age and live longer, the incidence of the disease is expected to balloon. Alzheimer’s is considered a death sentence that progressively steals one’s memory and independence. In the past few years, new diagnostics have been employed to detect the disease earlier.

Clinical drug trials are offering new hope for slowing the progression of the disease.

Alzheimer’s disease facts:

  • It is caused by abnormal formation of plaques and tangles in the brain that contain amyloid and tau proteins, which eventually cause damage and loss of brain cells.
  • Age (65+) is number one risk for the disease; 10% risk at age 65; 50% at 85
  • Hypertension, diabetes, hypercholesterolemia and heart disease also linked to the disease.
  • Risk is 1 in 6 for women in their 60s and older, while risk of breast cancer is 1 in 11.
  • Use of PET scans since 2012 to image plaques and make definitive diagnosis, studies currently underway in Southwest Florida to develop PET tracer for tangles.

Cognitive Aging chart

  • Mild memory loss can be a normal part of aging, severe interference with our lives makes it a disease.
  • Symptoms of Alzheimer’s disease do not show until 15 to 20 years after the disease has begun.
  • No current cure or treatment for Alzheimer’s disease, although new findings very encouraging to potentially prevent disease progression.
  • Clinical trials locally – contributing to Alzheimer’s research

Aducanumab, is a new drug currently in clinical trials, is an antibody designed to bind to amyloid and help clear it from the brain. Studies show monthly infusion of man-made antibodies has the potential to decrease the amyloid load and slow the disease from progressing. This is first breakthrough in treatment since the discovery of plaques and tangles in 1906.

For more information call the Neuropsychiatric Research Center of Southwest Florida at 239-939-7777 or visit neuropsychstudies.com.

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