Chaotic lake getting fence and securityWhat we learned about Cape Coral’s water crisis after a ride along
LEHIGH ACRES Chaotic lake getting fence and security Now, with all the negative attention it has gotten, some think putting up a fence is a great way to keep that bad activity out.
CAPE CORAL What we learned about Cape Coral’s water crisis after a ride along On Friday, WINK News got to ride along to see just what people are doing that could be wasting water.
FORT MYERS Students affected by COVID-19 able to graduate for the first time For many young people, COVID stripped away one of their greatest rites of passage: graduation.
Deadly crash on State Road 29 in Hendry County Authorities are at the scene of a deadly crash on State Road 29 in Hendry County on Friday afternoon.
Celebrating Free Comic Book Day in SWFL JP Sports store manager Jonathan Powell said this is a generational event that brings families together to reminisce on comics and other hobby-related knickknacks.
FORT MYERS Group rescues dogs before getting put down in Lee County Our animal shelters are packed with amazing puppies who have the sole desire to be loved.
FORT MYERS FGCU student beats all odds and is able to graduate Nearly four years ago, Marisa Manning had her heart set on going to Florida Gulf Coast University but never thought she’d find her passion for studying parasites.
FORT MYERS Victim in MLK Blvd. shooting identified as social media influencer The victim of the Martin Luther King Boulevard shooting has been identified as a local social media influencer.
FORT MYERS Could a Ferris wheel in downtown Fort Myers work? Right now, there are talks to bring a Ferris wheel to downtown Fort Myers, but several things are still up in the air.
LITTLE HICKORY BAY Improving ‘Hell’s Gate’ safety, a notoriously dangerous waterway for boaters A push to make an area known as “Hell’s Gate” safer since it’s a dangerous stretch of water with several blind corners within Little Hickory Bay.
Fixing failed back surgeries More than a million and a half people in the U.S. undergo back surgery each year. However, classic back surgery has one of the highest failure rates of any surgery.
WINK NEWS Getting an inside look at the FEMA discount controversy Picking up the pieces after Hurricane Ian has been difficult for many and moving on can impact our wallets.
FGCU FGCU pitcher Dylan Wolff playing for hometown team after labrum injury FGCU pitcher Dylan Wolff is living the dream playing for the hometown team after he overcame a labrum injury.
LEHIGH ACRES Frustrated Lehigh parents want action after violent school fights go viral online Violence at a Lehigh Acres Middle school was captured and posted online.
Turtle Club beachfront restaurant relaunches in Naples After a series of private friends and family events this week, The Turtle Club will reopen May 5 and begin taking reservations again May 6.
LEHIGH ACRES Chaotic lake getting fence and security Now, with all the negative attention it has gotten, some think putting up a fence is a great way to keep that bad activity out.
CAPE CORAL What we learned about Cape Coral’s water crisis after a ride along On Friday, WINK News got to ride along to see just what people are doing that could be wasting water.
FORT MYERS Students affected by COVID-19 able to graduate for the first time For many young people, COVID stripped away one of their greatest rites of passage: graduation.
Deadly crash on State Road 29 in Hendry County Authorities are at the scene of a deadly crash on State Road 29 in Hendry County on Friday afternoon.
Celebrating Free Comic Book Day in SWFL JP Sports store manager Jonathan Powell said this is a generational event that brings families together to reminisce on comics and other hobby-related knickknacks.
FORT MYERS Group rescues dogs before getting put down in Lee County Our animal shelters are packed with amazing puppies who have the sole desire to be loved.
FORT MYERS FGCU student beats all odds and is able to graduate Nearly four years ago, Marisa Manning had her heart set on going to Florida Gulf Coast University but never thought she’d find her passion for studying parasites.
FORT MYERS Victim in MLK Blvd. shooting identified as social media influencer The victim of the Martin Luther King Boulevard shooting has been identified as a local social media influencer.
FORT MYERS Could a Ferris wheel in downtown Fort Myers work? Right now, there are talks to bring a Ferris wheel to downtown Fort Myers, but several things are still up in the air.
LITTLE HICKORY BAY Improving ‘Hell’s Gate’ safety, a notoriously dangerous waterway for boaters A push to make an area known as “Hell’s Gate” safer since it’s a dangerous stretch of water with several blind corners within Little Hickory Bay.
Fixing failed back surgeries More than a million and a half people in the U.S. undergo back surgery each year. However, classic back surgery has one of the highest failure rates of any surgery.
WINK NEWS Getting an inside look at the FEMA discount controversy Picking up the pieces after Hurricane Ian has been difficult for many and moving on can impact our wallets.
FGCU FGCU pitcher Dylan Wolff playing for hometown team after labrum injury FGCU pitcher Dylan Wolff is living the dream playing for the hometown team after he overcame a labrum injury.
LEHIGH ACRES Frustrated Lehigh parents want action after violent school fights go viral online Violence at a Lehigh Acres Middle school was captured and posted online.
Turtle Club beachfront restaurant relaunches in Naples After a series of private friends and family events this week, The Turtle Club will reopen May 5 and begin taking reservations again May 6.
FILE – This Thursday, Feb. 25, 2021 file photo shows vials for the Moderna and Pfizer COVID-19 vaccines at a temporary clinic in Exeter, N.H. In September, 2021, the Food and Drug Administration approved extra doses of Pfizer’s original COVID-19 vaccine after studies showed it still works well enough against the delta variant. And the FDA is weighing evidence for boosters of the original Moderna and Johnson & Johnson vaccines. (AP Photo/Charles Krupa) More COVID-19 booster shots may be on the way — but when it’s your turn, you’ll get an extra dose of the original vaccine, not one updated to better match the extra-contagious delta variant. And that has some experts wondering if the booster campaign is a bit of a missed opportunity to target delta and its likely descendants. “Don’t we want to match the new strains that are most likely to circulate as closely as possible?” Dr. Cody Meissner of Tufts Medical Center, an adviser to the Food and Drug Administration, challenged Pfizer scientists recently. “I don’t quite understand why this is not delta because that’s what we’re facing right now,” fellow adviser Dr. Patrick Moore of the University of Pittsburgh said last week as government experts debated whether it’s time for Moderna boosters. He wondered if such a switch would be particularly useful to block mild infection. The simple answer: The FDA last month OK’d extra doses of Pfizer’s original recipe after studies showed it still works well enough against delta — and those doses could be rolled out right away. Now the FDA is weighing evidence for boosters of the original Moderna and Johnson & Johnson vaccines. “It’s less churn and burn on the manufacturing” to only switch formulas when it’s really necessary, said FDA vaccine chief Dr. Peter Marks. But Pfizer and Moderna are hedging their bets. They’re already testing experimental doses customized to delta and another variant, learning how to rapidly tweak the formula in case a change eventually is needed — for today’s mutants or a brand new one. The tougher question for regulators is how they’d decide if and when to ever order such a switch. What we know so far: CURRENT VACCINES ARE WORKING EVEN AGAINST DELTA Vaccines used in the U.S. remain strongly effective against hospitalization and death from COVID-19, even after the delta variant took over, but authorities hope to shore up waning protection against less severe infection and for high-risk populations. Studies show an extra dose of the original formulas revs up virus-fighting antibodies that fend off infection, including antibodies that target delta. MIGHT A DELTA-SPECIFIC BOOSTER WORK EVEN BETTER? Vaccines target the spike protein that coats the coronavirus. Mutations in that protein made delta more contagious but to the immune system, it doesn’t look all that different, said virus expert Richard Webby of St. Jude Children’s Research Hospital. That means there’s no guarantee a delta-specific booster would protect any better, said University of Pennsylvania immunologist John Wherry. Waiting for studies to settle that question — and if necessary, brewing updated doses — would have delayed rolling out boosters to people deemed to need them now. Still, because delta is now the dominant version of the virus worldwide it almost certainly will be a common ancestor for whatever evolves next in a mostly unvaccinated world, said Trevor Bedford, a biologist and genetics expert at the Fred Hutchinson Cancer Research Center. A delta-updated vaccine would “help to provide a buffer against those additional mutations,” he said. Bedford is paid by the Howard Hughes Medical Institute, which also supports The Associated Press Health and Science Department. TWEAKING THE RECIPE The Pfizer and Moderna vaccines are made with a piece of genetic code called messenger RNA that tells the body to make harmless copies of the spike protein so it’s trained to recognize the virus. Updating the formula merely requires swapping out the original genetic code with mRNA for a mutated spike protein. Both companies first experimented with tweaked doses against a mutant that emerged in South Africa, the beta variant, that has been the most vaccine-resistant to date, more so than the delta variant. Lab tests showed the updated shots produced potent antibodies. But the beta variant didn’t spread widely. Now the companies have studies underway of fully vaccinated people who agreed to test a booster dose tweaked to match delta. Moderna’s studies also include some shots that combine protection against more than one version of the coronavirus — much like today’s flu vaccines work against multiple influenza strains. The mRNA vaccines are considered the easiest kind to tweak but some other vaccine makers also are exploring how to change their recipes if necessary. WHY STUDY UPDATED SHOTS IF THEY’RE NOT YET NEEDED? Moderna’s Dr. Jacqueline Miller told an FDA advisory panel last week the company is studying variant-specific boosters now to learn if they offer advantages, and to be ready if they’re needed. And Penn’s Wherry said it is critical to carefully analyze how the body reacts to updated shots because the immune system tends to “imprint” a stronger memory of the first virus strain it encounters. That raises questions about whether a subtly different booster would prompt a temporary jump in antibodies the body’s made before — or the bigger goal, a broader and more durable response that might even be better positioned for the next mutations to come along. NO RULES YET FOR MAKING A SWITCH “What is the tipping point?” asked Webby, who is part of a World Health Organization network that tracks influenza evolution. “A lot of what is going to need to go into that decision making is just going to be learned by experience, unfortunately.” Bedford said now is the time to decide what drop in vaccine effectiveness would trigger a formula change, just as is done with flu vaccines every year. That’s important not just if a dramatically worse variant suddenly develops. Like many scientists, Bedford expects the coronavirus to eventually evolve from a global crisis into a regular threat every winter — which might mean more regular boosters, maybe even yearly in combination with the flu shot. Timing between shots matters, too, Wherry noted. “Your boostability may actually improve with longer intervals between stimulation,” he said. While scientists have learned a lot about the coronavirus, “the story’s not finished yet and we don’t know what the last chapters say.” ___ The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Department of Science Education. The AP is solely responsible for all content.