Bonita Springs residents alarmed after car break-insLee Deputies work to track down transient sex offenders who fail to register
BONITA SPRINGS Bonita Springs residents alarmed after car break-ins A Bonita Springs homeowner is sleeping with one eye open after her social security card was stolen from her car, an incident caught on video.
LEE COUNTY Lee Deputies work to track down transient sex offenders who fail to register WINK News Anchor Corey Lazar goes on patrol with Lee County Deputies in search of transient sex offenders who don’t register.
FORT MYERS Exclusive: Florida Warriors president talks misunderstanding with city On Friday, the president of Florida Warriors Hockey got a letter saying that starting July 1, his program’s rink access at the Fort Myers Skatium would be cut from 48 hours a month to only eight hours a month.
CHARLOTTE, N.C. (AP) 3 law officers killed, 5 others wounded trying to serve warrant in North Carolina, authorities say Three law enforcement officers serving a warrant for a felon wanted for possessing a firearm were killed and five other officers were wounded Monday in a shootout at a Charlotte, North Carolina, home, police said.
CAPE CORAL Massive fire leaves Cape Coral businesses in shambles Several fire rescue trucks are responding to a structure fire at a commercial building in Cape Coral.
NORTH FORT MYERS North Fort Myers residents concerned over abandoned boat A day out in the water turned into an alarming discovery for one North Fort Myers family.
FORT MYERS Fort Myers first responders stress safety after rollover crash Fort Myers fire department officials are pointing to safety and awareness following a recent rollover crash on Palm Beach Blvd. and Oasis Way.
NAPLES FSU pitcher Jacob Marlowe’s determined heart is on the mound Former Barron Collier ace, now FSU pitcher Jacob Marlowe is recovering from two open heart surgeries in five days.
Contrasting Lee, Collier and Charlotte homicide rates to nationwide numbers The Wall Street Journal says nationwide homicide rates have dropped by 20% compared to the numbers from 2023.
New program to make life more manageable for Parkinson’s patients A new program, backed by research, was created using the power of spin cycling to redefine the fight against Parkinson’s.
Medicaid class action gets go-ahead A federal judge has cleared the way for a class-action lawsuit that alleges Florida did not properly inform people before dropping them from the Medicaid program after a COVID-19 public health emergency ended.
FORT MYERS New downtown Fort Myers parking options coming soon Two new spots are coming for you to park on nights and weekends in downtown Fort Myers, but you’ll still have to pay.
LEHIGH ACRES Caught on Camera: Family ‘sucker-punched’ in Lehigh Acres brawl A woman is speaking out about a conflict she was involved in at Barefoot Lake.
Miracle Moment: Christina Soriero Doctors diagnosed 22-year-old Christina Soriero with non-Hodgkin’s lymphoma when she was just 18. A time in her life when the only thing she should have been dealing with was senioritis and getting ready for life after high school.
DeSantis signs bill impacting new mothers and jury duty Florida Gov. Ron DeSantis has signed a bill that will impact new mothers and their eligibility to serve on jury duty.
BONITA SPRINGS Bonita Springs residents alarmed after car break-ins A Bonita Springs homeowner is sleeping with one eye open after her social security card was stolen from her car, an incident caught on video.
LEE COUNTY Lee Deputies work to track down transient sex offenders who fail to register WINK News Anchor Corey Lazar goes on patrol with Lee County Deputies in search of transient sex offenders who don’t register.
FORT MYERS Exclusive: Florida Warriors president talks misunderstanding with city On Friday, the president of Florida Warriors Hockey got a letter saying that starting July 1, his program’s rink access at the Fort Myers Skatium would be cut from 48 hours a month to only eight hours a month.
CHARLOTTE, N.C. (AP) 3 law officers killed, 5 others wounded trying to serve warrant in North Carolina, authorities say Three law enforcement officers serving a warrant for a felon wanted for possessing a firearm were killed and five other officers were wounded Monday in a shootout at a Charlotte, North Carolina, home, police said.
CAPE CORAL Massive fire leaves Cape Coral businesses in shambles Several fire rescue trucks are responding to a structure fire at a commercial building in Cape Coral.
NORTH FORT MYERS North Fort Myers residents concerned over abandoned boat A day out in the water turned into an alarming discovery for one North Fort Myers family.
FORT MYERS Fort Myers first responders stress safety after rollover crash Fort Myers fire department officials are pointing to safety and awareness following a recent rollover crash on Palm Beach Blvd. and Oasis Way.
NAPLES FSU pitcher Jacob Marlowe’s determined heart is on the mound Former Barron Collier ace, now FSU pitcher Jacob Marlowe is recovering from two open heart surgeries in five days.
Contrasting Lee, Collier and Charlotte homicide rates to nationwide numbers The Wall Street Journal says nationwide homicide rates have dropped by 20% compared to the numbers from 2023.
New program to make life more manageable for Parkinson’s patients A new program, backed by research, was created using the power of spin cycling to redefine the fight against Parkinson’s.
Medicaid class action gets go-ahead A federal judge has cleared the way for a class-action lawsuit that alleges Florida did not properly inform people before dropping them from the Medicaid program after a COVID-19 public health emergency ended.
FORT MYERS New downtown Fort Myers parking options coming soon Two new spots are coming for you to park on nights and weekends in downtown Fort Myers, but you’ll still have to pay.
LEHIGH ACRES Caught on Camera: Family ‘sucker-punched’ in Lehigh Acres brawl A woman is speaking out about a conflict she was involved in at Barefoot Lake.
Miracle Moment: Christina Soriero Doctors diagnosed 22-year-old Christina Soriero with non-Hodgkin’s lymphoma when she was just 18. A time in her life when the only thing she should have been dealing with was senioritis and getting ready for life after high school.
DeSantis signs bill impacting new mothers and jury duty Florida Gov. Ron DeSantis has signed a bill that will impact new mothers and their eligibility to serve on jury duty.
FILE – A sign for the Food and Drug Administration is displayed outside their offices in Silver Spring, Md., on Dec. 10, 2020. According to research published Sunday, April 7, 2024, in the Journal of the American Medical Association, most cancer drugs granted accelerated approval by the FDA, meant to give patients early access to promising drugs, do not demonstrate such benefits within five years. (AP Photo/Manuel Balce Ceneta, File) The U.S. Food and Drug Administration’s accelerated approval program is meant to give patients early access to promising drugs. But how often do these drugs actually improve or extend patients’ lives? In a new study, researchers found that most cancer drugs granted accelerated approval do not demonstrate such benefits within five years. “Five years after the initial accelerated approval, you should have a definitive answer,” said Dr. Ezekiel Emanuel, a cancer specialist and bioethicist at the University of Pennsylvania who was not involved in the research. “Thousands of people are getting those drugs. That seems a mistake if we don’t know whether they work or not.” The program was created in 1992 to speed access to HIV drugs. Today, 85% of accelerated approvals go to cancer drugs. It allows the FDA to grant early approval to drugs that show promising initial results for treating debilitating or fatal diseases. In exchange, drug companies are expected to do rigorous testing and produce better evidence before gaining full approval. Patients get access to drugs earlier, but the tradeoff means some of the medications don’t pan out. It’s up to the FDA or the drugmaker to withdraw disappointing drugs, and sometimes the FDA has decided that less definitive evidence is good enough for a full approval. The new study found that between 2013 and 2017, there were 46 cancer drugs granted accelerated approval. Of those, 63% were converted to regular approval even though only 43% demonstrated a clinical benefit in confirmatory trials. The research was published in the Journal of the American Medical Association and discussed at the American Association for Cancer Research annual meeting in San Diego on Sunday. It’s unclear how much cancer patients understand about drugs with accelerated approval, said study co-author Dr. Edward Cliff of Harvard Medical School. “We raise the question: Is that uncertainty being conveyed to patients?” Cliff said. Drugs that got accelerated approval may be the only option for patients with rare or advanced cancers, said Dr. Jennifer Litton of MD Anderson Cancer Center in Houston, who was not involved in the study. It’s important for doctors to carefully explain the evidence, Litton said. “It might be shrinking of tumor. It might be how long the tumor stays stable,” Litton said. “You can provide the data you have, but you shouldn’t overpromise.” Congress recently updated the program, giving the FDA more authority and streamlining the process for withdrawing drugs when companies don’t meet their commitments. The changes allow the agency “to withdraw approval for a drug approved under accelerated approval, when appropriate, more quickly,” FDA spokesperson Cherie Duvall-Jones wrote in an email. The FDA can now require that a confirmatory trial be underway when it grants preliminary approval, which speeds up the process of verifying whether a drug works, she said.