Hot and humid Thursday before evening isolated storms impact coastal communitiesGov. DeSantis to hold a news conference in Jacksonville
the weather authority Hot and humid Thursday before evening isolated storms impact coastal communities The Weather Authority is tracking a humid Thursday morning with high afternoon temperatures and evening coastal isolated storms.
Jacksonville Gov. DeSantis to hold a news conference in Jacksonville Florida Gov. Ron DeSantis is set to hold a news conference in Jacksonville.
FORT MYERS BEACH Sea turtle nesting season begins in Fort Myers Beach Sea turtle nesting season has officially begun, and the FWC wants to remind visitors about the fragility of the young reptiles.
BAREFOOT LAKE Neighbors react to chaos at Barefoot Lake Imagine being scared to leave your home on the weekends. Ana and Anrik understand the feeling all too well.
CAPE CORAL The story of Ollie’s Pub and what kept it open through years of hardships Before Ollie’s housed weekly events, packed to the brim with artwork and home to many, it was a simple dream and an empty space.
Most Wanted Wednesday: Southwest Florida’s most wanted suspects for May 1, 2024 Here are some of Southwest Florida’s most wanted suspects for May 1, 2024.
FORT MYERS BEACH Remembering Fort Myers Beach ‘Mayor’ Brad Benson To know Brad Benson was to know a legend. He recently passed away at the age of 71 after battling health issues.
CAPE CORAL Proposed Cape Coral City Council meeting time change fails In a 4 to 4 vote, the motion to move Cape Coral meeting times from 4:30 to 9 a.m. failed.
Greater Dunbar initiative begins A duplex that has been around since the 1960s and is filled with generations of memories is being demolished.
Caught on camera: funnel clouds, hail and more during thunderstorm Wednesday’s thunderstorms storms have produced hail and funnel clouds.
SOUTHWEST FLORIDA New mammography guidelines Breast cancer is much easier to treat when it’s caught early.
CAPE CORAL Cape Coral church picking up the pieces after massive fire Calvary Connection ministries is unrecognizable after a massive fire swept through a Cape Coral Complex on Monday.
CAPE CORAL Day Two of FEMA code compliance hearings in Cape Coral Another 50 people were summoned Wednesday for the second day of code compliance hearings before the special magistrate.
PUNTA GORDA Cracking down on vapes in Charlotte County schools Vaping is taking over, and that’s why three Charlotte County High schools are testing out vape sensors.
State lawmakers want to hear your opinion on voting in Lee County Right now, everyone votes for or against all five of the Lee Commissioners, but they’re talking about changing the system so that each commissioner represents a specific part of the county.
the weather authority Hot and humid Thursday before evening isolated storms impact coastal communities The Weather Authority is tracking a humid Thursday morning with high afternoon temperatures and evening coastal isolated storms.
Jacksonville Gov. DeSantis to hold a news conference in Jacksonville Florida Gov. Ron DeSantis is set to hold a news conference in Jacksonville.
FORT MYERS BEACH Sea turtle nesting season begins in Fort Myers Beach Sea turtle nesting season has officially begun, and the FWC wants to remind visitors about the fragility of the young reptiles.
BAREFOOT LAKE Neighbors react to chaos at Barefoot Lake Imagine being scared to leave your home on the weekends. Ana and Anrik understand the feeling all too well.
CAPE CORAL The story of Ollie’s Pub and what kept it open through years of hardships Before Ollie’s housed weekly events, packed to the brim with artwork and home to many, it was a simple dream and an empty space.
Most Wanted Wednesday: Southwest Florida’s most wanted suspects for May 1, 2024 Here are some of Southwest Florida’s most wanted suspects for May 1, 2024.
FORT MYERS BEACH Remembering Fort Myers Beach ‘Mayor’ Brad Benson To know Brad Benson was to know a legend. He recently passed away at the age of 71 after battling health issues.
CAPE CORAL Proposed Cape Coral City Council meeting time change fails In a 4 to 4 vote, the motion to move Cape Coral meeting times from 4:30 to 9 a.m. failed.
Greater Dunbar initiative begins A duplex that has been around since the 1960s and is filled with generations of memories is being demolished.
Caught on camera: funnel clouds, hail and more during thunderstorm Wednesday’s thunderstorms storms have produced hail and funnel clouds.
SOUTHWEST FLORIDA New mammography guidelines Breast cancer is much easier to treat when it’s caught early.
CAPE CORAL Cape Coral church picking up the pieces after massive fire Calvary Connection ministries is unrecognizable after a massive fire swept through a Cape Coral Complex on Monday.
CAPE CORAL Day Two of FEMA code compliance hearings in Cape Coral Another 50 people were summoned Wednesday for the second day of code compliance hearings before the special magistrate.
PUNTA GORDA Cracking down on vapes in Charlotte County schools Vaping is taking over, and that’s why three Charlotte County High schools are testing out vape sensors.
State lawmakers want to hear your opinion on voting in Lee County Right now, everyone votes for or against all five of the Lee Commissioners, but they’re talking about changing the system so that each commissioner represents a specific part of the county.
MGN WASHINGTON (AP) – The Food and Drug Administration on Friday approved a first-of-a-kind drug that lowers artery-clogging cholesterol more than older drugs that have been prescribed for decades. The drug from Sanofi and Regeneron Pharmaceuticals Inc. offers an important new option for millions of patients at high risk of heart disease. But the drug’s sky-high price tag – $14,600 per year – is certain to escalate debate about the cost of breakthrough drugs and who should take them. Praluent is the first in a new class of biotech medications that use a novel approach to lower bad, or LDL, cholesterol. The drugs are considered the first major advance in treatment since the introduction of statin drugs more than 20 years ago, and analysts expect them to generate billions in sales. But the prospect of introducing highly-expensive, injectable drugs for one of the most common medical conditions is drawing concerns from health insurers, doctors and employers. Especially since generic statin pills are now available for as little as a dime a day. More than 73 million U.S. adults, or nearly one-third, have high LDL cholesterol, according to the Centers for Disease Control and Prevention. Those patients have twice the risk of heart disease, the leading cause of death worldwide. The FDA approved Praluent for two groups of patients at highest risk of heart problems: – patients with abnormally high LDL cholesterol caused by an inherited condition – patients with high LDL cholesterol and a history of heart attack, stroke, chest pain and related conditions Sanofi estimates those groups account for 8 to 10 million patients in the U.S. The drug’s $40-a-day price is even higher than many analyst predictions, which centered on $10,000 per year. In an interview Friday, Sanofi executive Dr. Jay Edelberg said the $14,600-a-year price reflects the “value to the health care system and the value to individual patients.” He noted that estimated costs for a patient who has suffered a heart attack or similar cardiovascular problem range from $50,000 to $119,000 over 1 year. But experts say more data is needed to establish if Praluent’s cholesterol-lowering ability actually translates into fewer heart problems and deaths. Sanofi and Regeneron are conducting an 18,000-patient study to answer that question, but it won’t be complete until 2017. Until then, many experts say new drugs like Praluent should be limited to the highest risk patients. “What we know so far is that they reduce cholesterol really well, but what we’re not sure about is whether they actually reduce someone’s risk,” said Dr. Harlan Krumholz, a Yale University cardiologist. “I think the wisest thing is to be cautious about their use and reserve them for people who have no other choice.” An estimated 6.3 million U.S. patients cannot control their LDL levels with statins alone, according to medical surveys. And another 3.3 million are thought to be unable to tolerate statins due to side effects, but there are no formal criteria to identify these patients. As such, experts say more research is needed to define the group. “I think we need to be clear what qualifies for statin intolerance,” Dr. Neil Stone, a cardiologist at Northwestern University, said. “What moves you from an inexpensive, generic statin to a very expensive new drug that doesn’t have near the track record of the statin?” The FDA is scheduled to rule on a similar drug from Amgen by Aug. 27. Pfizer’s entry into the field is expected to launch in 2018 or later. All three drugs lower low-density lipoprotein, or LDL, cholesterol more powerfully and in a different way than statins. They block a substance called PCSK9, which interferes with the liver’s ability to remove cholesterol from the blood. Adding the new drugs to older statins reduces LDL cholesterol by about 40 percent to 60 percent. Statins alone generally lower levels of the wax-like substance by about 25 to 35 percent. Statistical analyses published earlier this year suggest patients taking PCSK9 drugs have half the risk of dying or suffering a heart problem as patients receiving statins or older drugs. But definitive studies are still ongoing. For now, several factors could limit use of the drugs. They must be self-injected by patients, with Praluent dosed every two weeks. Also their price is expected to face pushback from insurers and other companies that manage drug expenses. Pharmacy benefit manager, CVS Caremark, has warned that if 10 million U.S. patients ultimately take PCSK9 drugs it could result in well over $100 billion in new drug spending. “The one thing you can say for sure is that these medications are going to add substantially to the overall cost of health care,” said Troyen Brennan, CVS’ chief medical officer. But analyst predictions for the drugs are more modest, at least initially. Credit Suisse analyst Vamil Divan estimates sales for the entire class – including drugs from Amgen and Pfizer – will reach $10 billion by 2019. Pharmaceutical research firm GlobalData projects global sales of $17.8 billion by 2023.