ALVA Woodpeckers build home in Alva woman’s house You may have heard of squatters, but this woman is dealing with squawkers. Who needs a rooster to wake up when you have woodpeckers?
FORT MYERS Man claims he was trapped in a high-rise for 5 days A 77-year-old man wants justice after he claims he spent days trapped on the 24th floor of a high-rise apartment building.
PUNTA GORDA Charlotte Correctional prisoner arrested for death of another inmate State Attorney Amira Fox convened a grand jury, which decided to move forward with a case against a Charlotte Correctional inmate.
SANIBEL Construction near Dairy Queen eagle nest on Sanibel raises concerns While many eagle nests may be a bit difficult to see, one nest has always been a favorite for Sanibel residents and tourists.
The environmental effects of artificial sweeteners Experts are studying how the foods we eat affect the environment, especially after we flush our waste down the toilet.
Victim reacts to man exposing himself to her Ring camera You get a notification on your phone from your ring camera app that someone is at the door, only to find out it is someone exposing themselves. It’s the last thing victim Maria Kivi wanted or expected to see last week.
LEE COUNTY The art of capturing your eye and drawing you in How do you capture young, hip, trendy, fun, movers and shakers, all in a pose? We take you behind the scenes of a Gulfshore Life cover shoot.
FORT MYERS The lives of two SJC Boxers changed in the ring Two SJC Boxers, Mario Nunez and Arbon Kurtishi, help each other in the ring as each of them had their lives changed because of boxing.
FORT MYERS Chlamydia cases rising sharply in Lee County If you think about a crowded space- something with more than 250 people- if it’s in Lee county, statistically one person has chlamydia.
SANIBEL Sanibel resort day passes hope to get more business on the island A pass will allow vacationers to hang out at a Sanibel beach club for a day in hopes of drumming up some business.
Voting equipment tested ahead of Lee County elections Voting equipment is being tested in Lee County. This is to ensure all ballots are printed and counted correctly for the upcoming election.
Collier County teen assaulted after leaving party The teen has been charged and the sheriff’s office said they’re aware that many believe felony charges are in order, but under Florida law, there are very specific criteria that must be met for felony charges to be filed.
WINK weather team watching tropical wave over Atlantic Ocean The Weather Authority is watching a tropical disturbance over the Central Atlantic Ocean.
CAPE CORAL Cape Coral drug bust leads investigators to fake fentanyl, cash and guns Cape Coral man arrest on drug charges. Investigators said they found, guns, drugs, and more than $32,000 in Richard Riley’s home.
NAPLES Naples youth flag football team to compete in Ohio tournament This weekend, the Naples Lunatics Green will compete in the Superhero Sports tournament in Canton, Ohio.
ALVA Woodpeckers build home in Alva woman’s house You may have heard of squatters, but this woman is dealing with squawkers. Who needs a rooster to wake up when you have woodpeckers?
FORT MYERS Man claims he was trapped in a high-rise for 5 days A 77-year-old man wants justice after he claims he spent days trapped on the 24th floor of a high-rise apartment building.
PUNTA GORDA Charlotte Correctional prisoner arrested for death of another inmate State Attorney Amira Fox convened a grand jury, which decided to move forward with a case against a Charlotte Correctional inmate.
SANIBEL Construction near Dairy Queen eagle nest on Sanibel raises concerns While many eagle nests may be a bit difficult to see, one nest has always been a favorite for Sanibel residents and tourists.
The environmental effects of artificial sweeteners Experts are studying how the foods we eat affect the environment, especially after we flush our waste down the toilet.
Victim reacts to man exposing himself to her Ring camera You get a notification on your phone from your ring camera app that someone is at the door, only to find out it is someone exposing themselves. It’s the last thing victim Maria Kivi wanted or expected to see last week.
LEE COUNTY The art of capturing your eye and drawing you in How do you capture young, hip, trendy, fun, movers and shakers, all in a pose? We take you behind the scenes of a Gulfshore Life cover shoot.
FORT MYERS The lives of two SJC Boxers changed in the ring Two SJC Boxers, Mario Nunez and Arbon Kurtishi, help each other in the ring as each of them had their lives changed because of boxing.
FORT MYERS Chlamydia cases rising sharply in Lee County If you think about a crowded space- something with more than 250 people- if it’s in Lee county, statistically one person has chlamydia.
SANIBEL Sanibel resort day passes hope to get more business on the island A pass will allow vacationers to hang out at a Sanibel beach club for a day in hopes of drumming up some business.
Voting equipment tested ahead of Lee County elections Voting equipment is being tested in Lee County. This is to ensure all ballots are printed and counted correctly for the upcoming election.
Collier County teen assaulted after leaving party The teen has been charged and the sheriff’s office said they’re aware that many believe felony charges are in order, but under Florida law, there are very specific criteria that must be met for felony charges to be filed.
WINK weather team watching tropical wave over Atlantic Ocean The Weather Authority is watching a tropical disturbance over the Central Atlantic Ocean.
CAPE CORAL Cape Coral drug bust leads investigators to fake fentanyl, cash and guns Cape Coral man arrest on drug charges. Investigators said they found, guns, drugs, and more than $32,000 in Richard Riley’s home.
NAPLES Naples youth flag football team to compete in Ohio tournament This weekend, the Naples Lunatics Green will compete in the Superhero Sports tournament in Canton, Ohio.
(CREDIT: CBS News) Brigham and Women’s Hospital will test the safety and efficacy of a nasal vaccine aimed at preventing and slowing Alzheimer’s disease, the Boston hospital announced Tuesday. The start of the small, Phase I clinical trial comes after nearly 20 years of research led by Howard L. Weiner, MD, co-director of the Ann Romney Center for Neurologic Diseases at the hospital. The trial will include 16 participants between the ages of 60 and 85, all with early symptomatic Alzheimer’s but otherwise generally healthy. They will receive two doses of the vaccine one week apart, the hospital said in a press release. The participants will enroll from the Ann Romney Center. A Phase I clinical trial is designed to establish the safety and dosage for a potential new medication. If it goes well, a much larger trial would be needed to test its effectiveness. The vaccine uses a substance called Protollin, which stimulates the immune system. “Protollin is designed to activate white blood cells found in the lymph nodes on the sides and back of the neck to migrate to the brain and trigger clearance of beta amyloid plaques — one of the hallmarks of AD [Alzheimer’s disease],” the hospital explains. It notes that Protollin has been found to be safe in other vaccines. “The launch of the first human trial of a nasal vaccine for Alzheimer’s is a remarkable milestone,” said Weiner in the hospital’s press release. “Over the last two decades, we’ve amassed preclinical evidence suggesting the potential of this nasal vaccine for AD. If clinical trials in humans show that the vaccine is safe and effective, this could represent a nontoxic treatment for people with Alzheimer’s, and it could also be given early to help prevent Alzheimer’s in people at risk.” The researchers say they aim to “determine the safety and tolerability of the nasal vaccine” in the trial and observe how Protollin affects participants’ immune response, including how it affects their white blood cells. “The immune system plays a very important role in all neurologic diseases,” Weiner added. “And it’s exciting that after 20 years of preclinical work, we can finally take a key step forward toward clinical translation and conduct this landmark first human trial.” “Research in this area has paved the way for us to pursue a whole new avenue for potentially treating not only AD, but also other neurodegenerative diseases,” said Tanuja Chitnis, MD, professor of neurology at Brigham and Women’s Hospital and principal investigator of the trial. I-Mab Biopharma and Jiangsu Nhwa Pharmaceutical are responsible for developing, manufacturing and commercializing Protollin. Medical researchers around the world have been working for years to develop new drugs to treat or slow Alzheimer’s, the most common cause of dementia, which affects an estimated 6 million Americans. But many of the experimental medications that once seemed promising in early studies have not panned out, leaving patients and their families with few good treatment options. In June, the FDA approved the first new drug for Alzheimer’s in 20 years, Biogen’s Aduhelm. However, the decision sparked controversy following warnings from independent advisers that the much-debated drug had not been shown to help slow the brain-destroying disease and carries the risk of serious side effects.